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DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1

In between the period of transplantation and revascularization, pancreatic islets are exposed to low-oxygen and low-nutrient conditions. In the present study we mimicked those conditions in vitro to study the involvement of different cell death processes, release of danger-associated molecular patte...

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Detalles Bibliográficos
Autores principales: Paredes-Juarez, Genaro A., Sahasrabudhe, Neha M., Tjoelker, Reina S., de Haan, Bart J., Engelse, Marten A., de Koning, Eelco J. P., Faas, Marijke M., de Vos, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588515/
https://www.ncbi.nlm.nih.gov/pubmed/26419792
http://dx.doi.org/10.1038/srep14623