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A covalent homodimer probing early oligomers along amyloid aggregation

Early oligomers are crucial in amyloid aggregation; however, due to their transient nature they are among the least structurally characterized species. We focused on the amyloidogenic protein beta2-microglobulin (β2m) whose early oligomers are still a matter of debate. An intermolecular interaction...

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Detalles Bibliográficos
Autores principales: Halabelian, Levon, Relini, Annalisa, Barbiroli, Alberto, Penco, Amanda, Bolognesi, Martino, Ricagno, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588566/
https://www.ncbi.nlm.nih.gov/pubmed/26420657
http://dx.doi.org/10.1038/srep14651