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A covalent homodimer probing early oligomers along amyloid aggregation
Early oligomers are crucial in amyloid aggregation; however, due to their transient nature they are among the least structurally characterized species. We focused on the amyloidogenic protein beta2-microglobulin (β2m) whose early oligomers are still a matter of debate. An intermolecular interaction...
Autores principales: | Halabelian, Levon, Relini, Annalisa, Barbiroli, Alberto, Penco, Amanda, Bolognesi, Martino, Ricagno, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588566/ https://www.ncbi.nlm.nih.gov/pubmed/26420657 http://dx.doi.org/10.1038/srep14651 |
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