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Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism

Genomic instability and altered metabolism are key features of most cancers. Recent studies suggest that metabolic reprogramming is part of a systematic response to cellular DNA damage. Thus, defining the molecules that fine-tune metabolism in response to DNA damage will enhance our understanding of...

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Detalles Bibliográficos
Autores principales: Jeong, Seung Min, Haigis, Marcia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588717/
https://www.ncbi.nlm.nih.gov/pubmed/26420294
http://dx.doi.org/10.14348/molcells.2015.0167