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Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism
Genomic instability and altered metabolism are key features of most cancers. Recent studies suggest that metabolic reprogramming is part of a systematic response to cellular DNA damage. Thus, defining the molecules that fine-tune metabolism in response to DNA damage will enhance our understanding of...
Autores principales: | Jeong, Seung Min, Haigis, Marcia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588717/ https://www.ncbi.nlm.nih.gov/pubmed/26420294 http://dx.doi.org/10.14348/molcells.2015.0167 |
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