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The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

Background: The DNA methylation-based ‘epigenetic clock’ correlates strongly with chronological age, but it is currently unclear what drives individual differences. We examine cross-sectional and longitudinal associations between the epigenetic clock and four mortality-linked markers of physical and...

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Detalles Bibliográficos
Autores principales: Marioni, Riccardo E, Shah, Sonia, McRae, Allan F, Ritchie, Stuart J, Muniz-Terrera, Graciela, Harris, Sarah E, Gibson, Jude, Redmond, Paul, Cox, Simon R, Pattie, Alison, Corley, Janie, Taylor, Adele, Murphy, Lee, Starr, John M, Horvath, Steve, Visscher, Peter M, Wray, Naomi R, Deary, Ian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588858/
https://www.ncbi.nlm.nih.gov/pubmed/25617346
http://dx.doi.org/10.1093/ije/dyu277