Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation

Background: Epigenome-wide association scans (EWAS) are under way for many complex human traits, but EWAS power has not been fully assessed. We investigate power of EWAS to detect differential methylation using case-control and disease-discordant monozygotic (MZ) twin designs with genome-wide DNA me...

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Detalles Bibliográficos
Autores principales: Tsai, Pei-Chien, Bell, Jordana T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Miscellaneous
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588864/
https://www.ncbi.nlm.nih.gov/pubmed/25972603
http://dx.doi.org/10.1093/ije/dyv041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588864/
https://www.ncbi.nlm.nih.gov/pubmed/25972603
http://dx.doi.org/10.1093/ije/dyv041

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