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Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation
Background: Epigenome-wide association scans (EWAS) are under way for many complex human traits, but EWAS power has not been fully assessed. We investigate power of EWAS to detect differential methylation using case-control and disease-discordant monozygotic (MZ) twin designs with genome-wide DNA me...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588864/ https://www.ncbi.nlm.nih.gov/pubmed/25972603 http://dx.doi.org/10.1093/ije/dyv041 |