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Association between perinatal methylation of the neuronal differentiation regulator HES1 and later childhood neurocognitive function and behaviour

Background Early life environments induce long-term changes in neurocognitive development and behaviour. In animal models, early environmental cues affect neuropsychological phenotypes via epigenetic processes but, as yet, there is little direct evidence for such mechanisms in humans. Method We exam...

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Detalles Bibliográficos
Autores principales: Lillycrop, Karen A, Costello, Paula M, Teh, Ai Ling, Murray, Robert J, Clarke-Harris, Rebecca, Barton, Sheila J, Garratt, Emma S, Ngo, Sherry, Sheppard, Allan M, Wong, Johnny, Dogra, Shaillay, Burdge, Graham C, Cooper, Cyrus, Inskip, Hazel M, Gale, Catharine R, Gluckman, Peter D, Harvey, Nicholas C, Chong, Yap-Seng, Yap, Fabian, Meaney, Michael J, Rifkin-Graboi, Anne, Holbrook, Joanna D, Godfrey, Keith M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588869/
https://www.ncbi.nlm.nih.gov/pubmed/25906782
http://dx.doi.org/10.1093/ije/dyv052