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Immunomodulatory effect of peritumorally administered interferon-beta on melanoma through tumor-associated macrophages

An imbalance of immunosuppressive cells and cytotoxic cells plays an important role in the tumor-bearing host. Together with regulatory T cells (Tregs), tumor-associated macrophages (TAMs) play roles in maintaining the tumor microenvironment. Since interferon beta (IFN-β) has been clinically used fo...

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Detalles Bibliográficos
Autores principales: Kakizaki, Aya, Fujimura, Taku, Furudate, Sadanori, Kambayashi, Yumi, Yamauchi, Takeshi, Yagita, Hideo, Aiba, Setsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589056/
https://www.ncbi.nlm.nih.gov/pubmed/26451326
http://dx.doi.org/10.1080/2162402X.2015.1047584