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Interferon-λ and interleukin-22 cooperate for the induction of interferon-stimulated genes and control of rotavirus infection

The epithelium is the major entry point for many viruses but the processes protecting barrier surfaces against viral infections are incompletely understood. We identify interleukin (IL)-22 produced by group 3 innate lymphoid cells (ILC3s) as an amplifier of interferon (IFN)-λ signaling, a synergism...

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Detalles Bibliográficos
Autores principales: Hernández, Pedro P., Mahlakoiv, Tanel, Yang, Ines, Schwierzeck, Vera, Nguyen, Nam, Guendel, Fabian, Gronke, Konrad, Ryffel, Bernhard, Hoelscher, Christoph, Dumoutier, Laure, Renauld, Jean-Christophe, Suerbaum, Sebastian, Staeheli, Peter, Diefenbach, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589158/
https://www.ncbi.nlm.nih.gov/pubmed/26006013
http://dx.doi.org/10.1038/ni.3180