Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver

The source of new hepatocytes in the uninjured liver has remained an open question. By lineage tracing using the Wnt-responsive gene Axin2, we identify a population of proliferating and self-renewing cells adjacent to the central vein in the liver lobule. These pericentral cells express the early li...

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Detalles Bibliográficos
Autores principales: Wang, Bruce, Zhao, Ludan, Fish, Matt, Logan, Catriona Y., Nusse, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589224/
https://www.ncbi.nlm.nih.gov/pubmed/26245375
http://dx.doi.org/10.1038/nature14863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589224/
https://www.ncbi.nlm.nih.gov/pubmed/26245375
http://dx.doi.org/10.1038/nature14863

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