Cargando…
Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver
The source of new hepatocytes in the uninjured liver has remained an open question. By lineage tracing using the Wnt-responsive gene Axin2, we identify a population of proliferating and self-renewing cells adjacent to the central vein in the liver lobule. These pericentral cells express the early li...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589224/ https://www.ncbi.nlm.nih.gov/pubmed/26245375 http://dx.doi.org/10.1038/nature14863 |