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Demethylation of Circulating Estrogen Receptor Alpha Gene in Cerebral Ischemic Stroke

BACKGROUND: Estrogen is involved in neuron plasticity and can promote neuronal survival in stroke. Its actions are mostly exerted via estrogen receptor alpha (ERα). Previous animal studies have shown that ERα is upregulated by DNA demethylation following ischemic injury. This study investigated the...

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Detalles Bibliográficos
Autores principales: Lin, Hsiu-Fen, Hsi, Edward, Liao, Yi-Chu, Chhor, Brian, Hung, Jessica, Juo, Suh-Hang H., Lin, Ruey-Tay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589317/
https://www.ncbi.nlm.nih.gov/pubmed/26422690
http://dx.doi.org/10.1371/journal.pone.0139608