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Demethylation of Circulating Estrogen Receptor Alpha Gene in Cerebral Ischemic Stroke
BACKGROUND: Estrogen is involved in neuron plasticity and can promote neuronal survival in stroke. Its actions are mostly exerted via estrogen receptor alpha (ERα). Previous animal studies have shown that ERα is upregulated by DNA demethylation following ischemic injury. This study investigated the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589317/ https://www.ncbi.nlm.nih.gov/pubmed/26422690 http://dx.doi.org/10.1371/journal.pone.0139608 |