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Molecular Binding Mechanism of TtgR Repressor to Antibiotics and Antimicrobials
A disturbing phenomenon in contemporary medicine is the prevalence of multidrug-resistant pathogenic bacteria. Efflux pumps contribute strongly to this antimicrobial drug resistance, which leads to the subsequent failure of clinical treatments. The TtgR protein of Pseudomonas putida is a HTH-type tr...
Autores principales: | Fernandez-Escamilla, Ana Maria, Fernandez-Ballester, Gregorio, Morel, Bertrand, Casares-Atienza, Salvador, Ramos, Juan Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589371/ https://www.ncbi.nlm.nih.gov/pubmed/26422008 http://dx.doi.org/10.1371/journal.pone.0138469 |
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