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A polycystin-centric view of cyst formation and disease: the polycystins revisited
It is 20 years since the identification of PKD1, the major gene mutated in autosomal dominant polycystic kidney disease (ADPKD), followed closely by the cloning of PKD2. These major breakthroughs have led in turn to a period of intense investigation into the function of the two proteins encoded, pol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589452/ https://www.ncbi.nlm.nih.gov/pubmed/26200945 http://dx.doi.org/10.1038/ki.2015.207 |