High-Throughput, Data-Rich Cellular RNA Device Engineering

Methods for rapidly assessing sequence-structure-function landscapes and developing conditional gene-regulatory devices are critical to our ability to manipulate and interface with biology. We describe a framework for engineering RNA devices from preexisting aptamers that exhibit ligand-responsive r...

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Detalles Bibliográficos
Autores principales: Townshend, Brent, Kennedy, Andrew B., Xiang, Joy S., Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589471/
https://www.ncbi.nlm.nih.gov/pubmed/26258292
http://dx.doi.org/10.1038/nmeth.3486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589471/
https://www.ncbi.nlm.nih.gov/pubmed/26258292
http://dx.doi.org/10.1038/nmeth.3486

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