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Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity

Corticotropin releasing hormone (CRH) production by the human placenta increases exponentially as pregnancy advances, and the rate of increase predicts gestational length. CRH gene expression is regulated by cAMP in trophoblasts through a cyclic AMP-response element (CRE), which changes its transcri...

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Detalles Bibliográficos
Autores principales: Pan, Xin, Bowman, Maria, Scott, Rodney J., Fitter, John, Nicholson, Richard C., Smith, Roger, Zakar, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589633/
https://www.ncbi.nlm.nih.gov/pubmed/26457081
http://dx.doi.org/10.1155/2015/861302