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Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity
Corticotropin releasing hormone (CRH) production by the human placenta increases exponentially as pregnancy advances, and the rate of increase predicts gestational length. CRH gene expression is regulated by cAMP in trophoblasts through a cyclic AMP-response element (CRE), which changes its transcri...
Autores principales: | Pan, Xin, Bowman, Maria, Scott, Rodney J., Fitter, John, Nicholson, Richard C., Smith, Roger, Zakar, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589633/ https://www.ncbi.nlm.nih.gov/pubmed/26457081 http://dx.doi.org/10.1155/2015/861302 |
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