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Direct chemotherapeutic dual drug delivery through intra-articular injection for synergistic enhancement of rheumatoid arthritis treatment

The effectiveness of systemic rheumatoid arthritis (RA) treatments is limited by difficulties in achieving therapeutic doses within articular joints. We evaluated the ability of intra-articular administration of injectable formulations to synergistically enhance repair of RA joints. Methotrexate-loa...

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Detalles Bibliográficos
Autores principales: Reum Son, A, Kim, Da Yeon, Hun Park, Seung, Yong Jang, Ja, Kim, Kyungsook, Ju Kim, Byoung, Yun Yin, Xiang, Ho Kim, Jae, Hyun Min, Byoung, Keun Han, Dong, Suk Kim, Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589689/
https://www.ncbi.nlm.nih.gov/pubmed/26424611
http://dx.doi.org/10.1038/srep14713