Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

Development of effective therapies for brain disorders has been hampered by a lack of translational cognitive testing methods. We present the first example of using the identical touchscreen-based cognitive test to assess mice and humans carrying disease-related genetic mutations. This new paradigm...

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Detalles Bibliográficos
Autores principales: Nithianantharajah, J., McKechanie, A. G., Stewart, T. J., Johnstone, M., Blackwood, D. H., St Clair, D., Grant, S. G. N., Bussey, T. J., Saksida, L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589696/
https://www.ncbi.nlm.nih.gov/pubmed/26423861
http://dx.doi.org/10.1038/srep14613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589696/
https://www.ncbi.nlm.nih.gov/pubmed/26423861
http://dx.doi.org/10.1038/srep14613

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