MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression

The transcription factor FOXP3 is essential for the differentiation and function of regulatory T cells (Treg). It is established that the transcription factor GATA-3 is induced in Treg cells under inflammatory conditions. GATA-3 stabilizes FOXP3 levels to avoid the differentiation of Treg cells into...

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Detalles Bibliográficos
Autores principales: Li, Dan, Kong, Chao, Tsun, Andy, Chen, Chen, Song, Huihui, Shi, Guochao, Pan, Wen, Dai, Dai, Shen, Nan, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589732/
https://www.ncbi.nlm.nih.gov/pubmed/26424054
http://dx.doi.org/10.1038/srep14615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589732/
https://www.ncbi.nlm.nih.gov/pubmed/26424054
http://dx.doi.org/10.1038/srep14615

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