Cargando…
MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression
The transcription factor FOXP3 is essential for the differentiation and function of regulatory T cells (Treg). It is established that the transcription factor GATA-3 is induced in Treg cells under inflammatory conditions. GATA-3 stabilizes FOXP3 levels to avoid the differentiation of Treg cells into...
Autores principales: | Li, Dan, Kong, Chao, Tsun, Andy, Chen, Chen, Song, Huihui, Shi, Guochao, Pan, Wen, Dai, Dai, Shen, Nan, Li, Bin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589732/ https://www.ncbi.nlm.nih.gov/pubmed/26424054 http://dx.doi.org/10.1038/srep14615 |
Ejemplares similares
-
Dual STAT-3 and IL-6R inhibition with stattic and tocilizumab decreases migration, invasion and proliferation of prostate cancer cells by targeting the IL-6/IL-6R/STAT-3 axis
por: Méndez-Clemente, Anibal, et al.
Publicado: (2022) -
Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop
por: Li, Huihui, et al.
Publicado: (2015) -
ERO1L promotes IL6/sIL6R signaling and regulates MUC16 expression to promote CA125 secretion and the metastasis of lung cancer cells
por: lei, Yuanyuan, et al.
Publicado: (2020) -
Differential Effects of IL-12 on Tregs and Non-Treg T Cells: Roles of IFN-γ, IL-2 and IL-2R
por: Zhao, Jingxian, et al.
Publicado: (2012) -
In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment
por: Ferreira, Ricardo C., et al.
Publicado: (2017)