An automated fitting procedure and software for dose-response curves with multiphasic features

In cancer pharmacology (and many other areas), most dose-response curves are satisfactorily described by a classical Hill equation (i.e. 4 parameters logistical). Nevertheless, there are instances where the marked presence of more than one point of inflection, or the presence of combined agonist and...

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Detalles Bibliográficos
Autores principales: Veroli, Giovanni Y. Di, Fornari, Chiara, Goldlust, Ian, Mills, Graham, Koh, Siang Boon, Bramhall, Jo L, Richards, Frances M., Jodrell, Duncan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589737/
https://www.ncbi.nlm.nih.gov/pubmed/26424192
http://dx.doi.org/10.1038/srep14701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589737/
https://www.ncbi.nlm.nih.gov/pubmed/26424192
http://dx.doi.org/10.1038/srep14701

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