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Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery

Anti-cytokine therapies have substantially improved the treatment of inflammatory and autoimmune diseases. Cytokine-targeting drugs are usually biologics such as antibodies or other engineered proteins. Production of biologics, however, is complex and intricate and therefore expensive which might li...

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Detalles Bibliográficos
Autores principales: Görtz, Dieter, Braun, Gerald S., Maruta, Yuichi, Djudjaj, Sonja, van Roeyen, Claudia R., Martin, Ina V., Küster, Andrea, Schmitz-Van de Leur, Hildegard, Scheller, Jürgen, Ostendorf, Tammo, Floege, Jürgen, Müller-Newen, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589789/
https://www.ncbi.nlm.nih.gov/pubmed/26423228
http://dx.doi.org/10.1038/srep14685