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The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex

BACKGROUND: Abl interactor (Abi) family proteins play significant roles in actin cytoskeleton organization through participation in the WAVE complex. Mammals possess three Abi proteins: Abi-1, Abi-2, and NESH/Abi-3. Abi-1 and Abi-2 were originally identified as Abl tyrosine kinase-binding proteins....

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Detalles Bibliográficos
Autores principales: Sekino, Saki, Kashiwagi, Yuriko, Kanazawa, Hitoshi, Takada, Kazuki, Baba, Takashi, Sato, Seiichi, Inoue, Hiroki, Kojima, Masaki, Tani, Katsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589964/
https://www.ncbi.nlm.nih.gov/pubmed/26428302
http://dx.doi.org/10.1186/s12964-015-0119-5