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Enhanced delivery of hydrophilic peptides in vitro by transdermal microneedle pretreatment
The aims of this study were to investigate the utility of solid microneedle arrays (150 µm in length) in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D(2)O flux. Four model peptides were used (Gly–Gln–Pro–Arg [tetrapeptide-3, 456.6 D...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590292/ https://www.ncbi.nlm.nih.gov/pubmed/26579370 http://dx.doi.org/10.1016/j.apsb.2013.12.011 |