Establishment of a selective evaluation method for DPP4 inhibitors based on recombinant human DPP8 and DPP9 proteins

Dipeptidyl peptidase 4 (DPP4) is recognised as an attractive anti-diabetic drug target, and several DPP4 inhibitors are already on the market. As members of the same gene family, dipeptidyl peptidase 8 (DPP8) and dipeptidyl peptidase 9 (DPP9) share high sequence and structural homology as well as fu...

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Detalles Bibliográficos
Autores principales: Liu, Jinglong, Huan, Yi, Li, Caina, Liu, Minzhi, Shen, Zhufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590293/
https://www.ncbi.nlm.nih.gov/pubmed/26579375
http://dx.doi.org/10.1016/j.apsb.2013.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590293/
https://www.ncbi.nlm.nih.gov/pubmed/26579375
http://dx.doi.org/10.1016/j.apsb.2013.12.007

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