Chitosan nanofiber scaffold improves bone healing via stimulating trabecular bone production due to upregulation of the Runx2/osteocalcin/alkaline phosphatase signaling pathway

Osteoblasts play critical roles in bone formation. Our previous study showed that chitosan nanofibers can stimulate osteoblast proliferation and maturation. This translational study used an animal model of bone defects to evaluate the effects of chitosan nanofiber scaffolds on bone healing and the p...

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Detalles Bibliográficos
Autores principales: Ho, Ming-Hua, Yao, Chih-Jung, Liao, Mei-Hsiu, Lin, Pei-I, Liu, Shing-Hwa, Chen, Ruei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590342/
https://www.ncbi.nlm.nih.gov/pubmed/26451104
http://dx.doi.org/10.2147/IJN.S90669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590342/
https://www.ncbi.nlm.nih.gov/pubmed/26451104
http://dx.doi.org/10.2147/IJN.S90669

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