Investigation of enzyme-sensitive lipid nanoparticles for delivery of siRNA to blood–brain barrier and glioma cells

Clinical applications of siRNA for treating disorders in the central nervous system require development of systemic stable, safe, and effective delivery vehicles that are able to cross the impermeable blood–brain barrier (BBB). Engineering nanocarriers with low cellular interaction during systemic c...

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Detalles Bibliográficos
Autores principales: Bruun, Jonas, Larsen, Trine B, Jølck, Rasmus I, Eliasen, Rasmus, Holm, René, Gjetting, Torben, Andresen, Thomas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590347/
https://www.ncbi.nlm.nih.gov/pubmed/26451106
http://dx.doi.org/10.2147/IJN.S87334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590347/
https://www.ncbi.nlm.nih.gov/pubmed/26451106
http://dx.doi.org/10.2147/IJN.S87334

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