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Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection
Oxidative stress (OS) stimulates autophagy in different cellular systems, but it remains controversial if this rule can be generalized. We have analyzed the effect of chronic OS induced by the parkinsonian toxin paraquat (PQ) on autophagy in astrocytoma cells and primary astrocytes, which represent...
Autores principales: | Janda, Elzbieta, Lascala, Antonella, Carresi, Cristina, Parafati, Maddalena, Aprigliano, Serafina, Russo, Vanessa, Savoia, Claudia, Ziviani, Elena, Musolino, Vincenzo, Morani, Federica, Isidoro, Ciro, Mollace, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590600/ https://www.ncbi.nlm.nih.gov/pubmed/26046590 http://dx.doi.org/10.1080/15548627.2015.1058683 |
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