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Cross-cancer profiling of molecular alterations within the human autophagy interaction network

Aberrant activation or disruption of autophagy promotes tumorigenesis in various preclinical models of cancer, but whether the autophagy pathway is a target for recurrent molecular alteration in human cancer patient samples is unknown. To address this outstanding question, we surveyed 211 human auto...

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Detalles Bibliográficos
Autores principales: Lebovitz, Chandra B, Robertson, A Gordon, Goya, Rodrigo, Jones, Steven J, Morin, Ryan D, Marra, Marco A, Gorski, Sharon M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590660/
https://www.ncbi.nlm.nih.gov/pubmed/26208877
http://dx.doi.org/10.1080/15548627.2015.1067362