The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells

Accumulation and aggregation of misfolded proteins is a hallmark of several diseases collectively known as proteinopathies. Autophagy has a cytoprotective role in diseases associated with protein aggregates. Age-related macular degeneration (AMD) is the most common neurodegenerative eye disease that...

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Detalles Bibliográficos
Autores principales: Johansson, Ida, Monsen, Vivi Talstad, Pettersen, Kristine, Mildenberger, Jennifer, Misund, Kristine, Kaarniranta, Kai, Schønberg, Svanhild, Bjørkøy, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590664/
https://www.ncbi.nlm.nih.gov/pubmed/26237736
http://dx.doi.org/10.1080/15548627.2015.1061170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590664/
https://www.ncbi.nlm.nih.gov/pubmed/26237736
http://dx.doi.org/10.1080/15548627.2015.1061170

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