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The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells
Accumulation and aggregation of misfolded proteins is a hallmark of several diseases collectively known as proteinopathies. Autophagy has a cytoprotective role in diseases associated with protein aggregates. Age-related macular degeneration (AMD) is the most common neurodegenerative eye disease that...
Autores principales: | Johansson, Ida, Monsen, Vivi Talstad, Pettersen, Kristine, Mildenberger, Jennifer, Misund, Kristine, Kaarniranta, Kai, Schønberg, Svanhild, Bjørkøy, Geir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590664/ https://www.ncbi.nlm.nih.gov/pubmed/26237736 http://dx.doi.org/10.1080/15548627.2015.1061170 |
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