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New genes drive the evolution of gene interaction networks in the human and mouse genomes

BACKGROUND: The origin of new genes with novel functions creates genetic and phenotypic diversity in organisms. To acquire functional roles, new genes must integrate into ancestral gene-gene interaction (GGI) networks. The mechanisms by which new genes are integrated into ancestral networks, and the...

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Detalles Bibliográficos
Autores principales: Zhang, Wenyu, Landback, Patrick, Gschwend, Andrea R., Shen, Bairong, Long, Manyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590697/
https://www.ncbi.nlm.nih.gov/pubmed/26424194
http://dx.doi.org/10.1186/s13059-015-0772-4