Comparative pharmacokinetics of tetramethylpyrazine phosphate in rat plasma and extracellular fluid of brain after intranasal, intragastric and intravenous administration

The purpose of this study was to compare the pharmacokinetic profiles of tetramethylpyrazine phosphate (TMPP) in plasma and extracellular fluid of the cerebral cortex of rats via three delivery routes: intranasal (i.n.), intragastric (i.g.) and intravenous (i.v.) administration. After i.n., i.g. and...

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Detalles Bibliográficos
Autores principales: Meng, Dongmei, Lu, Haoyang, Huang, Shanshan, Wei, Minyan, Ding, Pingtian, Xiao, Xianglin, Xu, Yuehong, Wu, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590719/
https://www.ncbi.nlm.nih.gov/pubmed/26579367
http://dx.doi.org/10.1016/j.apsb.2013.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590719/
https://www.ncbi.nlm.nih.gov/pubmed/26579367
http://dx.doi.org/10.1016/j.apsb.2013.12.009

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