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RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells

To increase the efficacy of currently used anti-cancer genotoxins, one of the current efforts is to find agents that can sensitize cancer cells to genotoxins so that the efficacious doses of genotoxins can be lowered to reduce deleterious side-effects. In this study, we reported that a synthetic Ras...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Zhang, Shenghua, He, Hongwei, Zhang, Caixia, Chen, Yi, Yu, Dongke, Chen, Jianhua, Shao, Rongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590723/
https://www.ncbi.nlm.nih.gov/pubmed/26579374
http://dx.doi.org/10.1016/j.apsb.2014.02.004