Preparation, Characterization and Evaluation of Quetiapine Fumarate Solid Lipid Nanoparticles to Improve the Oral Bioavailability

Quetiapine fumarate is an antipsychotic drug with poor oral bioavailability (9%) due to first-pass metabolism. Present work is an attempt to improve oral bioavailability of quetiapine fumarate by incorporating in solid lipid nanoparticles (SLN). Six quetiapine fumarate SLN formulations were develope...

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Detalles Bibliográficos
Autores principales: Narala, Arjun, Veerabrahma, Kishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590790/
https://www.ncbi.nlm.nih.gov/pubmed/26555970
http://dx.doi.org/10.1155/2013/265741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590790/
https://www.ncbi.nlm.nih.gov/pubmed/26555970
http://dx.doi.org/10.1155/2013/265741

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