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Preparation, Characterization, and In Vivo Evaluation of Olanzapine Poly(D,L-lactide-co-glycolide) Microspheres

The aim of this study was to prepare injectable depot formulations of Olanzapine using four poly(D,L-lactide-co-glycolide) (PLGA) polymers of varying molecular weight and copolymer composition, and evaluate in vivo performance in rats. In vivo release profiles from the formulations were governed chi...

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Detalles Bibliográficos
Autores principales: D'Souza, Susan, Faraj, Jabar A., Giovagnoli, Stefano, DeLuca, Patrick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590816/
https://www.ncbi.nlm.nih.gov/pubmed/26555996
http://dx.doi.org/10.1155/2013/831381