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Formulation and Characterization of Solid Dispersion Prepared by Hot Melt Mixing: A Fast Screening Approach for Polymer Selection

Solid dispersion is molecular dispersion of drug in a polymer matrix which leads to improved solubility and hence better bioavailability. Solvent evaporation technique was employed to prepare films of different combinations of polymers, plasticizer, and a modal drug sulindac to narrow down on a few...

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Detalles Bibliográficos
Autores principales: Enose, Arno A., Dasan, Priya K., Sivaramakrishnan, H., Shah, Sanket M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590819/
https://www.ncbi.nlm.nih.gov/pubmed/26556187
http://dx.doi.org/10.1155/2014/105382