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Targeting BCL2-Proteins for the Treatment of Solid Tumours
Due to their central role in the regulation of apoptosis, the antiapoptotic BCL2-proteins are highly promising targets for the development of novel anticancer treatments. To this end, several strategies have been developed to inhibit BCL2, BCL-X(L), BCL-w, and MCL1. While early clinical trials in ha...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590949/ https://www.ncbi.nlm.nih.gov/pubmed/26556430 http://dx.doi.org/10.1155/2014/943648 |