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Sequencing rare and common APOL1 coding variants to determine kidney disease risk

A third of African Americans with sporadic focal segmental glomerulosclerosis (FSGS) or HIV-associated nephropathy (HIVAN) do not carry APOL1 renal risk genotypes. This raises the possibility that other APOL1 variants may contribute to kidney disease. To address this question, we sequenced all APOL1...

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Detalles Bibliográficos
Autores principales: Limou, Sophie, Nelson, George W, Lecordier, Laurence, An, Ping, O’hUigin, Colm S, David, Victor A, Binns-Roemer, Elizabeth A, Guiblet, Wilfried M, Oleksyk, Taras K, Pays, Etienne, Kopp, Jeffrey B, Winkler, Cheryl A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591109/
https://www.ncbi.nlm.nih.gov/pubmed/25993319
http://dx.doi.org/10.1038/ki.2015.151