Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53

Multiple Sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system (CNS). Histopathological and radiological analysis revealed that neurodegeneration occurs early in the disease course. However, the pathological mechanisms involved in neurodegeneration are poorly unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Herold, Sabine, Kumar, Prateek, Wichert, Sven P., Kretzschmar, Benedikt, Bähr, Mathias, Rossner, Moritz J., Hein, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591258/
https://www.ncbi.nlm.nih.gov/pubmed/26426258
http://dx.doi.org/10.1371/journal.pone.0138852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591258/
https://www.ncbi.nlm.nih.gov/pubmed/26426258
http://dx.doi.org/10.1371/journal.pone.0138852

Ejemplares similares