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Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus

The absolute or relative lack of insulin is the key factor in the pathogenesis of diabetes mellitus. Although the connection between loss of function mutations of the WFS1 gene and DIDMOAD-syndrome including diabetes mellitus underpins the significance of wolframin in the pathogenesis, exact role of...

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Detalles Bibliográficos
Autores principales: Elek, Zsuzsanna, Németh, Nóra, Nagy, Géza, Németh, Helga, Somogyi, Anikó, Hosszufalusi, Nóra, Sasvári-Székely, Mária, Rónai, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591293/
https://www.ncbi.nlm.nih.gov/pubmed/26426397
http://dx.doi.org/10.1371/journal.pone.0139519