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Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine

Suppression of tumor metastasis is a key strategy for successful cancer interventions. Previous studies indicated that rapamycin (sirolimus) may promote tumor regression activity or enhance immune response against tumor targets. However, rapamycin also exhibits immunosuppressant effects and is hence...

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Detalles Bibliográficos
Autores principales: Lin, Tien-Jen, Liang, Wen-Miin, Hsiao, Pei-Wen, M. S, Pradeep, Wei, Wen-Chi, Lin, Hsin-Ting, Yin, Shu-Yi, Yang, Ning-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591294/
https://www.ncbi.nlm.nih.gov/pubmed/26426423
http://dx.doi.org/10.1371/journal.pone.0138335