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Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine
Suppression of tumor metastasis is a key strategy for successful cancer interventions. Previous studies indicated that rapamycin (sirolimus) may promote tumor regression activity or enhance immune response against tumor targets. However, rapamycin also exhibits immunosuppressant effects and is hence...
Autores principales: | Lin, Tien-Jen, Liang, Wen-Miin, Hsiao, Pei-Wen, M. S, Pradeep, Wei, Wen-Chi, Lin, Hsin-Ting, Yin, Shu-Yi, Yang, Ning-Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591294/ https://www.ncbi.nlm.nih.gov/pubmed/26426423 http://dx.doi.org/10.1371/journal.pone.0138335 |
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