Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers

To assess the value of exosomal miRNAs as biomarkers for Alzheimer disease (AD), the expression of microRNAs was measured in a plasma fraction enriched in exosomes by differential centrifugation, using Illumina deep sequencing. Samples from 35 persons with a clinical diagnosis of AD dementia were co...

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Detalles Bibliográficos
Autores principales: Lugli, Giovanni, Cohen, Aaron M., Bennett, David A., Shah, Raj C., Fields, Christopher J., Hernandez, Alvaro G., Smalheiser, Neil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591334/
https://www.ncbi.nlm.nih.gov/pubmed/26426747
http://dx.doi.org/10.1371/journal.pone.0139233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591334/
https://www.ncbi.nlm.nih.gov/pubmed/26426747
http://dx.doi.org/10.1371/journal.pone.0139233

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