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Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers
To assess the value of exosomal miRNAs as biomarkers for Alzheimer disease (AD), the expression of microRNAs was measured in a plasma fraction enriched in exosomes by differential centrifugation, using Illumina deep sequencing. Samples from 35 persons with a clinical diagnosis of AD dementia were co...
Autores principales: | Lugli, Giovanni, Cohen, Aaron M., Bennett, David A., Shah, Raj C., Fields, Christopher J., Hernandez, Alvaro G., Smalheiser, Neil R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591334/ https://www.ncbi.nlm.nih.gov/pubmed/26426747 http://dx.doi.org/10.1371/journal.pone.0139233 |
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