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Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects

BACKGROUND: Ventricular septal defects (VSDs) are the most common and simplest type of congenital heart diseases (CHDs). Animal studies have suggested that the downregulation of Yes-associated protein 1 (YAP1) during embryonic development causes VSD-associated CHDs. However, how YAP1 contributes to...

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Detalles Bibliográficos
Autores principales: Ye, Lincai, Yin, Meng, Xia, Yu, Jiang, Chuan, Hong, Haifa, Liu, Jinfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591351/
https://www.ncbi.nlm.nih.gov/pubmed/26426694
http://dx.doi.org/10.1371/journal.pone.0139712