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Long Standing Eculizumab Treatment without Anticoagulant Therapy in High-Risk Thrombogenic Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra-orphan disease affecting all hematopoietic cell types. The abnormality of red blood cells in this disease predisposes to intravascular complement-mediated hemolysis. Eculizumab is an orphan drug used to treat this rare disease. Thrombosis is the...

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Detalles Bibliográficos
Autores principales: Al-Jafar, Hassan A., AlDallal, Salma M., Askar, Haifa A., Aljeraiwi, Ali M., Al-Alansari, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591499/
https://www.ncbi.nlm.nih.gov/pubmed/26487933
http://dx.doi.org/10.4081/hr.2015.5927